ALTERAÇÕES LABORATORIAIS RELEVANTES DEVIDO AO USO DE INIBIDORES DA RECAPTAÇÃO DE SEROTONINA (ISRS)

Abstract

One of the main systems of the human body is the nervous system. It is composed of its cells, neurons. Neurons are responsible for transmission of nerve impulses through specialized proteins called neurotransmitters. There are several neurotransmitters with a specific purpose.Serotonin is one such neurotransmitter with inhibitory effect of conduct and modulating effect of psychic activity, responsible for the regulation of various activities such as sleep, mood, appetite, motor activity, etc. Depression is an emotional disorder characterized by deregulation of the feelings of joy and sadness and mood alteration (OLIVEIRA, 2005).Antidepressants are psychotropic drugs used in the treatment of this disease with the aim of restoring the emotional balance by increasing the availability of neurotransmitters in the synaptic cleft. A new class of antidepressants used recently is the inhibitors Selective serotonin reuptake inhibitors have advantages and not yet fully known how the interaction with the individual's metabolism and consequently with changes in laboratory analytes.Several studies have been and are being held for further clarification on these changes and it is known that this class of antidepressants alters mainly the thyroid hormones: T4 (thyroxine) and T3 (triiodothyronine) and the concentration of sodium in the body.